8 responses

  1. L
    May 15, 2016

    My veterinary clinic recently sent me a form letter saying that they would no longer be prescribing Tramadol for pain management.

    “We recommend alternative medication and therapies including gabapentin, acupuncture, and rehabilitation.”

    Reply

    • skeptvet
      May 15, 2016

      Well, I generally agree that oral tramadol is probably ineffective and the evidence for it is not much better than that for acupuncture, but that doesn’t make acupuncture a reasonable substitute. Gabapentin is probably effective for at least some kinds of pain. And rehabilitation, which is the veterinary version of physical therapy, should be helpful given that it clearly is in human medicine, but there is virtually no research in veterinary patients yet to show efficacy.

      Reply

  2. L
    May 16, 2016

    Rimadyl seems to be keeping him comfortable (he’s elderly) and wouldn’t be able to tolerate anything aggressive. I thought the tramadol had a bit of a sedative effect.
    Thanks for your reply.

    Reply

  3. dogowner
    May 22, 2016

    Wait, really? Does that mean my dog is on no pain control at all- she’s on 200mg/day of tramadol for her arthritis. Should I go back to the vet and discuss this? Is there any evidence you are aware of that I should bring in?

    Reply

    • skeptvet
      May 22, 2016

      There is research evidence that injectable tramadol has analgesic effects in dogs. However, as L pointed out, in humans oral tramadol works via a metabolite that dogs don’t make, so it’s unclear if it does anything given orally through other metabolites. Subjectively, many vets (myself included) feel it doesn’t work very well in practice, though this is difficult to assess. It may be appropriate to ass on to other pain control medications, but it really shouldn’t be used as the sole agent for pain control in my opinion.

      Reply

  4. L
    May 22, 2016

    My vet explained to me that the Tramadol works in humans cause it converts to an opiate, however the latest research on canines proves that they don’t convert it….so it may still have some sedative qualities. Anything that helps with anxiety decreases pain a little.
    Hope this helps. I’m sure the doctor can explain it better than I did.

    Reply

  5. Joseph Tein
    January 16, 2020

    Hi SkeptVet,

    I appreciate that we need to be careful about accepting claims for the efficacy of things; there’s always misguided, ignorant, superstitious or downright deceptive people out there touting all sorts of quackery. But I also want us to be careful with statements like “the evidence does not support acupuncture” or “lack of adequate scientific evidence …” or “lack of evidence to support significant objective effects.” None of these statements says that there IS evidence that acupuncture is not effective (or has maybe limited effectiveness in a few cases). The same goes for many other treatments, products, and feeding approaches. The lack of scientific evidence could just mean that nobody did the research. Purina isn’t going to fund a clinical trial to test balanced home-cooked diets against Dog Chow. The holistic vets don’t have the money to run extensive head-to-head trials on different diets or treatments, and the commercial Big Pet Food/Pharma companies, who have the money, have NO incentive to do that … it might take a bite out of their profits!! So, bottom line, when you state that “there is no evidence” for the effectiveness of a diet or treatment, you really should tell us clearly whether that means that there IS evidence that it is NOT effective, or just the research hasn’t been done. Thanks.

    Reply

    • skeptvet
      January 17, 2020

      Actually, that isn’t how science works. You can’t ever provide evidence something doesn’t work, you can only test it and either find evidence it does or fail to find such evidence. Proving a negative is a near impossibility.

      What often happens when you test something and it fails is that proponents of that therapy say that something was done wrong- the test, the procedure, the dose, etc. Fair enough, but then you have to do another test that takes that issue into account. You can do that a million times and never prove the treatment can’t ever work in some way on some patient. The problem is that this is a tremendous waste of time and resources, and medicine advances faster and more surely if we decide that after a reasonable amount of effort to find evidence something works, if we are unsuccessful then further testing and use of that therapy isn’t justified.

      Here’s a much longer discussion of the issue that, at some point, absence of evidence is evidence of absence.

      Reply

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