SkeptVet Posts
Metronidazole for Acute Diarrhea in Dogs: An Evidence-based Treatment?
Probiotic Fortiflora: Not apparently very helpful in preventing diarrhea in shelter animals
Encouraging studies on probiotics for canine diarrhea
Fecal Microbiome Testing- Anything to It?
No Good News for Veterinary ProbioticsThe efficacy of metronidazole.
Journal Articles
Candellone A, Cerquetella M, Girolami F, Badino P, Odore R. Acute Diarrhea in Dogs: Current Management and Potential Role of Dietary Polyphenols Supplementation. Antioxidants (Basel). 2020 Aug 9;9(8):725. doi: 10.3390/antiox9080725. PMID: 32784917; PMCID: PMC7465157.
Shmalberg J, Montalbano C, Morelli G, Buckley GJ. A Randomized Double Blinded Placebo-Controlled Clinical Trial of a Probiotic or Metronidazole for Acute Canine Diarrhea. Front Vet Sci. 2019 Jun 4;6:163. doi: 10.3389/fvets.2019.00163. PMID: 31275948; PMCID: PMC6593266.
Pignataro G, Di Prinzio R, Crisi PE, Belà B, Fusaro I, Trevisan C, De Acetis L, Gramenzi A. Comparison of the Therapeutic Effect of Treatment with Antibiotics or Nutraceuticals on Clinical Activity and the Fecal Microbiome of Dogs with Acute Diarrhea. Animals (Basel). 2021 May 21;11(6):1484. doi: 10.3390/ani11061484. PMID: 34063855; PMCID: PMC8223982.
Chaitman J, Ziese AL, Pilla R, Minamoto Y, Blake AB, Guard BC, Isaiah A, Lidbury JA, Steiner JM, Unterer S, Suchodolski JS. Fecal Microbial and Metabolic Profiles in Dogs With Acute Diarrhea Receiving Either Fecal Microbiota Transplantation or Oral Metronidazole. Front Vet Sci. 2020 Apr 16;7:192. doi: 10.3389/fvets.2020.00192. PMID: 32363202; PMCID: PMC7182012.
Langlois DK, Koenigshof AM, Mani R. Metronidazole treatment of acute diarrhea in dogs: A randomized double blinded placebo-controlled clinical trial. J Vet Intern Med. 2020 Jan;34(1):98-104. doi: 10.1111/jvim.15664. Epub 2019 Nov 19. PMID: 31742807; PMCID: PMC6979100.
Tong, J. O. P. (2019). In canine acute diarrhoea with no identifiable cause, does daily oral probiotic improve the clinical outcomes?. Veterinary Evidence, 4(4). https://doi.org/10.18849/ve.v4i4.252
Moreno AA, Parker VJ, Winston JA, Rudinsky AJ. Dietary fiber aids in the management of canine and feline gastrointestinal disease. J Am Vet Med Assoc. 2022 Oct 26;260(S3):S33-S45. doi: 10.2460/javma.22.08.0351. PMID: 36288203.
Moore, E., & Gordon-Evans, W. . (2022). Should we prescribe oral metronidazole or probiotics for acute gastroenteritis in dogs?. Veterinary Evidence, 7(2). https://doi.org/10.18849/ve.v7i2.393
Holden, R. and Brennan, M. (2021), Does metronidazole increase the speed of recovery in dogs with acute diarrhoea?. Veterinary Record, 188: 33-34. https://doi.org/10.1002/vetr.44
Nixon, SL, Rose, L, Muller, AT. Efficacy of an orally administered anti-diarrheal probiotic paste (Pro-Kolin Advanced) in dogs with acute diarrhea: A randomized, placebo-controlled, double-blinded clinical study. J Vet Intern Med. 2019; 33: 1286– 1294. https://doi.org/10.1111/jvim.15481
Chaitman, Jennifer, and Frédéric Gaschen. “Fecal microbiota transplantation in dogs.” Veterinary Clinics: Small Animal Practice 51.1 (2021): 219-233.
Rudinsky, Adam J., et al. “Randomized controlled trial demonstrates nutritional management is superior to metronidazole for treatment of acute colitis in dogs.” Journal of the American Veterinary Medical Association 260.S3 (2022): S23-S32.
