Author Archives: skeptvet

Lifespan and Healthspan

The goal of longevity therapies is to prolong both lifespan (the number of years an individual lives) and healthspan (the number of years free of significant disease or disability). Current preventative medical interventions, such as vaccines, have greatly increased lifespan, … Continue reading

Posted in Aging Science | 1 Comment

OncoK9 Liquid Biopsy: Should Your Dog have this Test?

It is really never a good sign when a miraculous new breakthrough in veterinary medicine is announced on the internet. That isn’t where true scientific breakthroughs show up. Legitimate science is a slow, detailed process where even brilliant, revolutionary ideas have … Continue reading

Posted in Science-Based Veterinary Medicine | 13 Comments

Telomeres & Aging

Each new discovery in aging biology generates a lot of excitement. Newly discovered mechanisms are sometimes enthusiastically promoted as dramatic breakthroughs that will transform the field and lead to powerful clinical therapies. Over time, our understanding of these new elements … Continue reading

Posted in Aging Science | Leave a comment

Measuring Aging: Epigenetic Clocks

Aging involves physical changes over time, but time is not the primary driver of these changes. Large-breed dogs age faster than small breed dogs, and there is great individual variation in the manifestations of aging. A key lesson we have … Continue reading

Posted in Aging Science | 4 Comments

Gabapentin: Is it useful for pain control in dogs and cats?

Veterinary medicine suffers from a chronic lack of scientific evidence to identify safe and effective treatments. We are authorized to used medicines approved for human or animal use on an off-label basis in other species or conditions because the Food … Continue reading

Posted in Science-Based Veterinary Medicine | 20 Comments

Lifespan & Body Size- Big Animals Live Longer, Except When They Don’t

One of the earliest recorded assertions that large animals live longer than small ones comes from Aristotle in 350 BC. Such unstructured observations have subsequently been supported by more rigorous scientific study. As this graph shows, there is a positive … Continue reading

Posted in Aging Science | 6 Comments

Stem Cell Therapies in Veterinary Medicine: Where are We Now?

I’ve written about stem cell therapies numerous times over the years, though not for quite a while. My conclusions were always along the lines of “promising but unproven.” This is one of those perfectly plausible therapies that I expect will … Continue reading

Posted in Science-Based Veterinary Medicine | 1 Comment

Can We Help Our Dogs to Live Longer & Healthier Lives?

One of the first logical questions for a good skeptic to ask when thinking about canine aging biology is whether it is plausible that we can extend lifespan (years lived) and healthspan (healthy years lived) in dogs. Is there reliable … Continue reading

Posted in Aging Science | 4 Comments

When to Spay Your Dog: SkeptVet and Dr. Andy Roark on the Cone of Shame Podcast

During my latest visit to the Cone of Shame Podcast with Dr. Andy Roark, we discuss when to spay your dog.

Posted in Presentations, Lectures, Publications & Interviews | 6 Comments

Grain-free Diets and Heart Disease in Dogs: Two New Studies

I have to admit, I didn’t think I would again be addressing the topic of diet-associated dilated cardiomyopathy (DCM) so soon after my recent podcast and post summarizing the debate. But the science around this topic is racing ahead, and there are two new … Continue reading

Posted in Nutrition | 4 Comments